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Anti-NALP12 (Polyclonal), ALEXA Fluor 594

Anti-NALP12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNALP12
SpecificityThis antibody reacts specifically with NALP12
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human NALP12
Gene ID91662
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information IRAK-1, Like all other NALP family members, NALP12, NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes, TRAF6 and RIPK1 in activated monocytes, also known as Monarch-1, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain, has a C-terminal leucine-rich repeat (LRR) region, May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK, NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3
Also known asNALP12 Polyclonal Antibody
Other nameAnti-NALP12 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNALP12
Short nameAnti-NALP12 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-NALP12 (polyclonal)
Alternative techniquepolyclonals
Identity 22938
Gene NLRP12
Long gene name NLR family pyrin domain containing 12
Synonyms gene NALP12
Synonyms gene name NACHT, leucine rich repeat and PYD containing 12
Synonyms name leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain
Locus 19q13, 42
Discovery year 2003-10-28
GenBank acession AY095146
Entrez gene record 91662
Pubmed identfication 12563287 12019269
RefSeq identity NM_144687
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000060776
Locus Specific Databases LRG_181

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