Anti-NALP4 (Polyclonal), ALEXA Fluor 594

Anti-NALP4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	NALP4
Specificity	C and E Mouse variants, including the A, NALP4, This antibody will detect multiple forms of NALP4
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human NALP4
Gene ID	147945
Swiss Prot	Q96MN2
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, and its subsequent degradation, suggesting that it operates at a point of convergence in these two cytokine signaling pathways, May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	PYPAF4 FLJ32126 PAN2 RNH2 CLR19, 5 CT58
Also known as	NALP4 Polyclonal Antibody
Other name	Anti-NALP4 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	NALP4
Short name	Anti-NALP4 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-NALP4 (polyclonal)
Alternative technique	polyclonals
Identity	22943
Gene	NLRP4
Long gene name	NLR family pyrin domain containing 4
Synonyms gene	NALP4
Synonyms gene name	NACHT, leucine rich repeat and PYD containing 4
Synonyms name	leucine rich repeat and pyrin domain containing 4 cancer/testis antigen 58 , nucleotide-binding oligomerization domain
Locus	19q13, 43
Discovery year	2003-10-28
GenBank acession	AF479747
Entrez gene record	147945
Pubmed identfication	12563287 12019269
RefSeq identity	NM_134444
Classification	NLR family Pyrin domain containing
Havana BLAST/BLAT	OTTHUMG00000181734

Anti-NALP4 (Polyclonal), ALEXA Fluor 594

Anti-NALP4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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