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Anti-NAT8B (Polyclonal), ALEXA Fluor 594

Anti-NAT8B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNAT8B
SpecificityThis antibody reacts specifically with NAT8B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human NAT8B
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A member of the camello family, A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, Human chromosome 2 consists of 237 million bases, NAT-8B (N-acetyltransferase 8B), NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13, Similarly, The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, a non-functional protein that is truncated in length, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, also known as CML2 (camello-like protein 2), as it causes the N-acetyltransferase to become disrupted, encodes over 1, is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation, sitosterolemia and Alstré, syndrome, which leads to a stop codon and subsequently, °, &permil, 2, 400 genes and makes up approximately 8% of the human genome, Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Hcml2 NAT8BP
Also known asNAT8B Polyclonal Antibody
Other nameAnti-NAT8B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNAT8B
Short nameAnti-NAT8B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-NAT8B (polyclonal)
Alternative techniquepolyclonals
Identity 30235
Gene NAT8B
Long gene name N-acetyltransferase 8B (putative, gene/pseudogene)
Synonyms gene name N-acetyltransferase 8B (gene/pseudogene) N-acetyltransferase 8B (GCN5-related, gene/pseudogene) , putative
Locus 2p13, 1
Discovery year 2006-10-24
GenBank acession BC069564
Entrez gene record 51471
Pubmed identfication 11397015 16395595 19011241
RefSeq identity NM_016347
Havana BLAST/BLAT OTTHUMG00000152811

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