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Anti-NCAM2 (Polyclonal), ALEXA Fluor 594

Anti-NCAM2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNCAM2
SpecificityThis antibody reacts specifically with NCAM2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human NCAM2
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information NCAM2 contains five immunoglobulin-like domains, NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells, NCAM2 is a member of the neural cell adhesion molecule (NCAM) family, NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development, Neither Stat1 nor Stat3 bind to this region, Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, The gene is expressed most strongly in human adult and fetal brain, a transmembrane domain and a cytoplasmic domain, despite sharing a consensus binding sequence with Stat5, this binding is induced by cytokines that activate Stat5, two Fibronectin type III domains, NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NCAM21 MGC51008
Also known asNCAM2 Polyclonal Antibody
Other nameAnti-NCAM2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNCAM2
Short nameAnti-NCAM2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-neural cellular adhesion molecule 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target NCAM2 and IDBG-1027 and ENSG00000154654 and 4685, NCAM2 and IDBG-630332 and ENSBTAG00000003301 and 535613, NCAM21, Ncam2 and IDBG-172510 and ENSMUSG00000022762 and 17968, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007413 and axonal fasciculation and biological process this GO :0007608 and sensory perception of smell and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030424 and axon and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, neural cell adhesion molecule 2
Identity 7657
Gene NCAM2
Long gene name neural cell adhesion molecule 2
Locus 21q21, 1
Discovery year 1997-04-25
Entrez gene record 4685
Pubmed identfication 9226371
RefSeq identity NM_004540
Classification Fibronectin type III domain containing I-set domain containing
Havana BLAST/BLAT OTTHUMG00000078121

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