Name : Anti-NDRG1 (Thr346) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN8453528442
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | NDRG1 Thr346 |
| Specificity | This antibody reacts specifically with NDRG1 (Thr346) |
| Modification | Phosphorylation |
| Modification site | Thr346 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human NDRG1 around the phosphorylation site of Thr346 |
| Gene ID | 10397 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | In colon, May have a growth inhibitory role, Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom, Reduced expression in adenocarcinomas compared to normal tissues, The protein encoded by this gene is a cytoplasmic protein involved in stress responses, Ubiquitous, and differentiation, and ovary tissues, cell growth, expressed most prominently in placental membranes and prostate, hormone responses, kidney, prostate and placental membranes, small intestine, the cells that border the lumen show the highest expression, This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DRG1 RTP TDD5 NDR1 |
| Also known as | NDRG1 (Thr346) Polyclonal Antibody |
| Other name | Anti-NDRG1 (Thr346) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | NDRG1 (Thr346) |
| Short name | Anti-NDRG1 (Thr346) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-N-v-myc myelocytomatosis viral oncogene homolog (avian) downstream regulated 1 (Thr346) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CAP43 and CMT4D and DRG-1 and DRG1 and GC4 and HMSNL and NDR1 and NMSL and PROXY1 and RIT42 and RTP and TARG1 and TDD5, NDRG1 and IDBG-36420 and ENSG00000104419 and 10397, NDRG1 and IDBG-644056 and ENSBTAG00000000711 and 504499, Ndrg1 and IDBG-146853 and ENSMUSG00000005125 and 17988, cadherin binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0043015 and gamma-tubulin binding and molecular function this GO :0045296 and cadherin binding and molecular function this GO :0045576 and mast cell activation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0055038 and recycling endosome membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071456 and cellular response to hypoxia and biological process this GO :0090232 and positive regulation of spindle checkpoint and biological process, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0008017 and microtubule binding and molecular function this GO :0008219 and cell death and biological process this GO :0010038 and response to metal ion and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0017137 and Rab GTPase binding and molecular function this GO :0030330 and DNA damage response, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008017: microtubule binding and also this GO :0017137: Rab GTPase binding and also this GO :0043015: gamma-tubulin binding and also this GO :0045296: cadherin binding, this GO :0008017: microtubule binding, this GO :0017137: Rab GTPase binding, this GO :0043015: gamma-tubulin binding, this GO :0045296: cadherin binding, N-myc downstream regulated 1 |
| Identity | 7679 |
| Gene | NDRG1 |
| Long gene name | N-myc downstream regulated 1 |
| Synonyms gene | CAP43 |
| Locus | 8q24, 22 |
| Discovery year | 1998-12-23 |
| GenBank acession | X92845 |
| Entrez gene record | 10397 |
| Pubmed identfication | 9251681 8939898 18455888 |
| Havana BLAST/BLAT | OTTHUMG00000164441 |
| Locus Specific Databases | Inherited Peripheral Neuropathies Mutation Database LRG_258 |