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Anti-NEDD4L (Ser342) (Polyclonal), ALEXA Fluor 594

Anti-NEDD4L (Ser342) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNEDD4L Ser342
SpecificityThis antibody reacts specifically with NEDD4L (Ser342)
ModificationPhosphorylation
Modification siteSer342
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human NEDD4L around the phosphorylation site of Ser342
Gene ID23327
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information EAAT1 or CLC5, Furthermore, Kv1, Nav1, Nav1, Nav1, Nav1, Nav1, This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation, and promotes the ubiquitination and degradation of SGK, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, 2, 3, 3, 5, 7, 8, E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0439 RSP5 NEDD4-2
Also known asNEDD4L (Ser342) Polyclonal Antibody
Other nameAnti-NEDD4L (Ser342) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNEDD4L (Ser342)
Short nameAnti-NEDD4L (Ser342) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, E3 ubiquitin protein ligase (Ser342) (polyclonal), developmentally down-regulated 4-like, antibody to-neural precursor cellular expressed
Alternative techniquepolyclonals
Alternative to gene target DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006513 and protein monoubiquitination and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007588 and excretion and biological process this GO :0009651 and response to salt stress and biological process this GO :0010038 and response to metal ion and biological process this GO :0010467 and gene expression and biological process this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010766 and negative regulation of sodium ion transport and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016032 and viral process and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0019058 and viral life cycle and biological process this GO :0019870 and potassium channel inhibitor activity and molecular function this GO :0019871 and sodium channel inhibitor activity and molecular function this GO :0030104 and water homeostasis and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0034765 and regulation of ion transmembrane transport and biological process this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0043162 and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060306 and regulation of membrane repolarization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0086005 and ventricular cardiac muscle cell action potential and biological process this GO :1901016 and regulation of potassium ion transmembrane transporter activity and biological process this GO :1901017 and negative regulation of potassium ion transmembrane transporter activity and biological process this GO :1901380 and negative regulation of potassium ion transmembrane transport and biological process this GO :1902306 and negative regulation of sodium ion transmembrane transport and biological process this GO :2000009 and negative regulation of protein localization to cell surface and biological process this GO :2000650 and negative regulation of sodium ion transmembrane transporter activity and biological process this GO :2000810 and regulation of tight junction assembly and biological process this GO :2001259 and positive regulation of cation channel activity and biological process this GO :2001288 and positive regulation of caveolin-mediated endocytosis and biological process, E3 ubiquitin protein ligase, NEDD4L and IDBG-3835 and ENSG00000049759 and 23327, NEDD4L and IDBG-644828 and ENSBTAG00000005412 and 510003, Nedd4l and IDBG-154290 and ENSMUSG00000024589 and 83814, developmentally down-regulated 4-like, hNEDD4-2 and NEDD4-2 and NEDD4, ion channel binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003085 and negative regulation of systemic arterial blood pressure and biological process this GO :0003254 and regulation of membrane depolarization and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0015459: potassium channel regulator activity and also this GO :0016874: ligase activity and also this GO :0017080: sodium channel regulator activity and also this GO :0019870: potassium channel inhibitor activity and also this GO :0019871: sodium channel inhibitor activity and also this GO :0044325: ion channel binding, this GO :0005515: protein binding, this GO :0015459: potassium channel regulator activity, this GO :0016874: ligase activity, this GO :0017080: sodium channel regulator activity, this GO :0019870: potassium channel inhibitor activity, this GO :0019871: sodium channel inhibitor activity, this GO :0044325: ion channel binding, 2 and RSP5, neural precursor cell expressed
Identity 7728
Gene NEDD4L
Long gene name E3 ubiquitin protein ligase , developmentally down-regulated 4-like, neural precursor cell expressed
Synonyms gene name developmentally down-regulated 4-like , neural precursor cell expressed
Locus 18q21, 31
Discovery year 2000-03-14
GenBank acession AF210730
Entrez gene record 23327
Pubmed identfication 10594025 11244092 18322022
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000179875

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