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Anti-NeuroD1 (Polyclonal), ALEXA Fluor 594

Anti-NeuroD1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNeuroD1
SpecificityThis antibody reacts specifically with NeuroD1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human NeuroD1
Gene ID4760
Swiss ProtQ13562
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also required for dendrite morphogenesis and maintenance in the cerebellar cortex, Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity), Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A, Contributes to the regulation of several cell differentiation pathways, Together with PAX6 or SIX3, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, inner ear sensory neurons, is required for the regulation of amacrine cell fate specification, like those that promote the formation of early retinal ganglion cells, Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BETA2 BHF-1 NeuroD bHLHa3 MODY6
Also known asNeuroD1 Polyclonal Antibody
Other nameAnti-NeuroD1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNeuroD1
Short nameAnti-NeuroD1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-neuronal differentiation 1 (polyclonal)
Alternative techniquepolyclonals
Identity 7762
Gene NEUROD1
Long gene name neuronal differentiation 1
Synonyms gene NEUROD
Synonyms gene name neurogenic differentiation 1
Synonyms name beta-cell E-box transactivator 2 neurogenic helix-loop-helix protein NEUROD
Locus 2q31, 3
Discovery year 1996-03-12
GenBank acession U50823
Entrez gene record 4760
Pubmed identfication 7754368 8786144
RefSeq identity NM_002500
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000132583

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