Anti-Nfasc186 (Polyclonal), ALEXA Fluor 594

Anti-Nfasc186 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Nfasc186
Specificity	This antibody reacts specifically with Nfasc186
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human Nfasc186
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Nfasc186 (Isoform 1) is expressed at the Nodes of Ranvier while the Nfasc155 (isoforms 2 and 3) are expressed in unmyelinated axons, Nfasc186 in neurons and Nfasc155 in glia, The establishment of paranodal axoglial junctions in myelinated nerves where voltage-gated sodium channels are concentrated at the nodes of Ranvier is determined by myelin-forming glia, The two isoforms of Neurofascin, These two major Neurofascins play essential roles in assembling the nodal and paranodal domains of myelinated axons and are essential for the transition to saltatory conduction in developing vertebrate nerves, are required for the assembly of these specialized domains, the other being Nfasc155, Nfasc186 (Neurofascin 186) is one of two alternatively spliced products of the Neurofascin (Nfasc) gene in rat
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	NF antibody NF186, NFASC, NFASC_HUMAN, NRCAML, Neurofascin
Also known as	Nfasc186 Polyclonal Antibody
Other name	Anti-Nfasc186 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Nfasc186
Short name	Anti-Nfasc186 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Nfasc186 (polyclonal)
Alternative technique	polyclonals

Anti-Nfasc186 (Polyclonal), ALEXA Fluor 594

Anti-Nfasc186 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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