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Anti-NG2 (Polyclonal), ALEXA Fluor 594

Anti-NG2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNG2
SpecificityThis antibody reacts specifically with NG2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human NG2
Gene ID1464
Swiss ProtQ6UVK1
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NG2 G16 RING5 RMA1
Also known asNG2 Polyclonal Antibody
Other nameAnti-NG2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNG2
Short nameAnti-NG2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-NG2 (polyclonal)
Alternative techniquepolyclonals
Identity 10068
Gene RNF5
Long gene name ring finger protein 5
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 5
Locus 6p21, 32
Discovery year 1997-10-16
GenBank acession U89336
Entrez gene record 6048
Pubmed identfication 9533025
RefSeq identity NM_006913
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000031093

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