Name : Anti-NHEDC2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6701048782
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | NHEDC2 |
| Specificity | This antibody reacts specifically with NHEDC2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human NHEDC2 |
| Gene ID | 133308 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | As a multi-pass membrane protein, Found in red blood cells, NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), NHEDC2 is expressed as two isoforms produced by alternative splicing events, NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane, NHEDC2 is required for bone resorption activity and osteoclast differentiation, also known as NHA2, is a 537 amino acid mitochondrial protein, Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ23984 NHA2 |
| Also known as | NHEDC2 Polyclonal Antibody |
| Other name | Anti-NHEDC2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | NHEDC2 |
| Short name | Anti-NHEDC2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-NHEDC2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25143 |
| Gene | SLC9B2 |
| Long gene name | solute carrier family 9 member B2 |
| Synonyms gene | NHEDC2 |
| Synonyms gene name | Na+/H+ exchanger domain containing 2 solute carrier family 9, cation proton antiporter 2), member 2 , member 2 solute carrier family 9, subfamily B (NHA2, subfamily B (cation proton antiporter 2) |
| Locus | 4q24 |
| Discovery year | 2007-05-15 |
| GenBank acession | AK172823 |
| Entrez gene record | 133308 |
| Pubmed identfication | 18600791 |
| RefSeq identity | NM_178833 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000131125 |