Filters

Anti-NLRP12 Antibody

Anti-NLRP12 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnti-NLRP12
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the anti-NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-NLRP12 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P59046
PurityAntigen affinity
Description CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes, MIM 608107) domain (PYD), Most short NALPs, NALP1 (MIM 606636), NALPs are implicated in the activation of proinflammatory caspases (e, The long NALP, a NACHT-associated domain (NAD), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD), and a C-terminal leucine-rich repeat (LRR) region, followed by a NACHT domain, have an N-terminal pyrin (MEFV, such as NALP12, NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family, g
ImmunogenThis anti-NLRP12 antibody was produced from rabbits immunized with human NLRP12 recombinant protein
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-NLRP12 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetNLRP12
Short nameAnti-NLRP12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name pyrin domain containing 12 (Antibody to), antibody to-NLR family
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, NLRP12 and IDBG-641617 and ENSBTAG00000038149 and 522018, NLRP12 and IDBG-67727 and ENSG00000142405 and 91662, Nlrp12 and IDBG-264083 and ENSMUSG00000078817 and 378425, cysteine-type endopeptidase activator activity involved in apoptotic process, pyrin domain containing 12, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009968 and negative regulation of signal transduction and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0036336 and dendritic cell migration and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045345 and positive regulation of MHC class I biosynthetic process and biological process this GO :0045381 and regulation of interleukin-18 biosynthetic process and biological process this GO :0045409 and negative regulation of interleukin-6 biosynthetic process and biological process this GO :0045751 and negative regulation of Toll signaling pathway and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050711 and negative regulation of interleukin-1 secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :1901223 and negative regulation of NIK/NF-kappaB signaling and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, NLR family
Identity 22938
Gene NLRP12
Long gene name NLR family pyrin domain containing 12
Synonyms gene NALP12
Synonyms gene name NACHT, leucine rich repeat and PYD containing 12
Synonyms RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3
Synonyms name leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain
Locus 19q13, 42
Discovery year 2003-10-28
GenBank acession AY095146
Entrez gene record 91662
Pubmed identfication 12563287 12019269
RefSeq identity NM_144687
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000060776
Locus Specific Databases LRG_181

Similar products

Subscribe to our Newsletter