Name : Anti- NLRX1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2614055256
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | NLRX1 |
| Specificity | This antibody reacts specifically with NLRX1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human NLR family member X1 |
| Gene ID | 79671 |
| Swiss Prot | Q86UT6 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as a negative regulator of MAVS-mediated antiviral responses, Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313), through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010), Participates in antiviral signaling |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NOD9 CLR11, 3 |
| Also known as | NLRX1 Polyclonal Antibody |
| Other name | Anti- NLRX1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | NLRX1 |
| Short name | Anti- NLRX1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, Antibody to NLRX1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 29890 |
| Gene | NLRX1 |
| Long gene name | NLR family member X1 |
| Synonyms name | X1 , leucine rich repeat containing X1 NOD-like receptor X1 NLR family, nucleotide-binding oligomerization domain |
| Locus | 11q23, 3 |
| Discovery year | 2006-12-08 |
| GenBank acession | AB094095 |
| Entrez gene record | 79671 |
| Pubmed identfication | 12766759 |
| RefSeq identity | NM_170722 |
| Classification | NLR family |
| Havana BLAST/BLAT | OTTHUMG00000154476 |