Name : Anti-NMDAR3A + 3B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5253220719
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | NMDAR3A + 3B |
| Specificity | This antibody reacts specifically with NMDAR3A + 3B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human NMDAR3A + 3B |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to 7, NR3B, NR3B functions in the brain as an excitatory glycine receptor, One such NMDA receptor, The kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, both of which contain glutamate-gated, cation-specific ion channels, is expressed in motor neurons and forms cation channels impermeable to calcium, modifying the normal role of glycine as an inhibitory neurotransmitter, neural development and neuro-degeneration, whereas the NMDA receptors exhibit slow kinesis of Ca2+ ions and a high permeability for Ca2+ ions, which can resist many open-channel blockers, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | GRIN3A, GRIN3B, Glutamate Receptor Ionotropic N methyl D aspartate 3B, Glutamate Receptor Ionotropic N-methyl-D-aspartate 3A, Glutamate Receptor Ionotropic N-methyl-D-aspartate 3B, NMD3A_HUMANã, NMD3B_HUMANï, NMDA Type Glutamate Receptor Subunit NR3B Precursor, NMDA receptor subunit 3A, NMDA receptor subunit 3B, NMDAR-L, NR3A, NR3B, &euro, ¼, &rsaquo, &sbquo, Glutamate Receptor Ionotropic N methyl D aspartate 3A |
| Also known as | NMDAR3A + 3B Polyclonal Antibody |
| Other name | Anti-NMDAR3A + 3B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | NMDAR3A + 3B |
| Short name | Anti-NMDAR3A + 3B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-NMDAR3A and 3B (polyclonal) |
| Alternative technique | polyclonals |