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Anti-Nociceptin receptor (Polyclonal), ALEXA Fluor 594

Anti-Nociceptin receptor (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNociceptin receptor
SpecificityThis antibody reacts specifically with Nociceptin receptor
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from mouse Nociceptin receptor
Gene ID18389
Swiss ProtP35377
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Plays a role in modulating nociception and the perception of pain, Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin, Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity, G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NOCIR ORL1 OOR KOR-3 NOPr
Also known asNociceptin receptor Polyclonal Antibody
Other nameAnti-Nociceptin receptor Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetNociceptin receptor
Short nameAnti-Nociceptin receptor (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Nociceptin receptor (polyclonal)
Alternative techniquepolyclonals
Identity 8155
Gene OPRL1
Long gene name opioid related nociceptin receptor 1
Synonyms gene name opiate receptor-like 1
Synonyms name LC132 receptor-like orphanin FQ receptor kappa3-related opioid receptor nociceptin/orphanin FQ receptor
Locus 20q13, 33
Discovery year 1996-05-28
Entrez gene record 4987
Pubmed identfication 8137918 17910740
RefSeq identity NM_182647
Classification Opioid receptors
Havana BLAST/BLAT OTTHUMG00000033027

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