Filters

Anti-OA1/GPR143 (Polyclonal), ALEXA Fluor 594

Anti-OA1/GPR143 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOA1/GPR143
SpecificityThis antibody reacts specifically with OA1/GPR143
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human OA1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding for OA1 cause ocular albinism, G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation), GPR143, OA1, They respond to a great variety of signaling molecules, also designated ocular albinism type 1 protein (OA1), an X-linked disorder mainly characterized by retinal hypopigmentation and visual impairment, are members of the largest protein family and play a role in many different stimulus-response pathways, including hormones, is a melanosomal protein expressed primarily in pigment cells, is detected exclusively in pigment cells, neurotransmitters and other proteins and peptides, which is a multi-pass membrane protein, G protein-coupled receptors (GPRs or GPCRs)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asOA1/GPR143 Polyclonal Antibody
Other nameAnti-OA1/GPR143 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOA1/GPR143
Short nameAnti-OA1/GPR143 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-OA1/GPR143 (polyclonal)
Alternative techniquepolyclonals
Identity 20145
Gene GPR143
Long gene name G protein-coupled receptor 143
Synonyms gene OA1
Synonyms gene name ocular albinism 1 (Nettleship-Falls)
Synonyms name ocular albinism 1
Locus Xp22, 2
Discovery year 2003-12-01
GenBank acession Z48804
Entrez gene record 4935
Pubmed identfication 7647783 10471510
RefSeq identity NM_000273
Classification 7TM orphan receptors
Havana BLAST/BLAT OTTHUMG00000021118
Locus Specific Databases Albinism Database Mutations of the OA1 Gene

Subscribe to our Newsletter