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Anti-OLIG1 (Polyclonal), ALEXA Fluor 594

Anti-OLIG1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOLIG1
SpecificityThis antibody reacts specifically with OLIG1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human OLIG1
Gene ID116448
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information OLIG proteins are candidates for molecular markers of human glial brain tumors, OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas, OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis, OLIG1 and OLIG2 interact with the Nkx-2, OLIG2 is more widely expressed in embryonic brain than OLIG1, Therefore, These interactions between OLIG proteins and Nkx-2, which are the most common primary malignancies of the human brain, which differ in tissue expression, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube, while OLIG3 is primarily expressed in non-neural tissues, 2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development, 2 homeodomain protein, The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BHLHB6 bHLHe21
Also known asOLIG1 Polyclonal Antibody
Other nameAnti-OLIG1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOLIG1
Short nameAnti-OLIG1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-OLIG1 (polyclonal)
Alternative techniquepolyclonals
Identity 16983
Gene OLIG1
Long gene name oligodendrocyte transcription factor 1
Synonyms name 6 , class B, helix-loop-helix protein, oligodendrocyte-specific bHLH transcription factor 1 oligodendrocyte lineage transcription factor 1 basic domain
Locus 21q22, 11
Discovery year 2001-12-04
GenBank acession AP000109
Entrez gene record 116448
Pubmed identfication 11526205
RefSeq identity NM_138983
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000065064

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