Name : Anti-Orai2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8616050517
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Orai2 |
| Specificity | This antibody reacts specifically with Orai2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Orai2 |
| Gene ID | 80228 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response, Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1, 4, 5-trisphosphate production and other Ca2+ mobilizing agents, Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CBCIP2 FLJ12474 FLJ14733 H_NH0514P08, 8 |
| Also known as | Orai2 Polyclonal Antibody |
| Other name | Anti-Orai2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Orai2 |
| Short name | Anti-Orai2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Orai2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 21667 |
| Gene | ORAI2 |
| Long gene name | ORAI calcium release-activated calcium modulator 2 |
| Synonyms gene | C7orf19 TMEM142B |
| Synonyms gene name | chromosome 7 open reading frame 19 transmembrane protein 142B |
| Synonyms name | CAP-binding protein complex interacting protein 2 |
| Locus | 7q22, 1 |
| Discovery year | 2003-07-09 |
| GenBank acession | AF258552 |
| Entrez gene record | 80228 |
| Pubmed identfication | 16582901 23890118 |
| RefSeq identity | NM_032831 |
| Classification | ORAI calcium release-activated calcium modulators |
| Havana BLAST/BLAT | OTTHUMG00000157722 |