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Anti-Orai2 (Polyclonal), ALEXA Fluor 594

Anti-Orai2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOrai2
SpecificityThis antibody reacts specifically with Orai2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Orai2
Gene ID80228
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response, Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1, 4, 5-trisphosphate production and other Ca2+ mobilizing agents, Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CBCIP2 FLJ12474 FLJ14733 H_NH0514P08, 8
Also known asOrai2 Polyclonal Antibody
Other nameAnti-Orai2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOrai2
Short nameAnti-Orai2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Orai2 (polyclonal)
Alternative techniquepolyclonals
Identity 21667
Gene ORAI2
Long gene name ORAI calcium release-activated calcium modulator 2
Synonyms gene C7orf19 TMEM142B
Synonyms gene name chromosome 7 open reading frame 19 transmembrane protein 142B
Synonyms name CAP-binding protein complex interacting protein 2
Locus 7q22, 1
Discovery year 2003-07-09
GenBank acession AF258552
Entrez gene record 80228
Pubmed identfication 16582901 23890118
RefSeq identity NM_032831
Classification ORAI calcium release-activated calcium modulators
Havana BLAST/BLAT OTTHUMG00000157722

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