Name : anti-ORAI3 Antibody [2H2G9]
Supplier : PROSCIENCE
Price :180
SKU : GEN7745166978
| Gene info | 2 and 3 channels were equally inhibited by extracellular Ca++, All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, However, Larger molecular weight bands are sometimes seen in SDS-PAGE, Na+ currents through ORAI1, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, ORAI3 is one of two mammalian homologs to ORAI1, This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2, a recently identified four-transmembrane spanning protein that is an essential component of CRAC, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2, indicating that each have similar affinities for Ca++ within the selectivity filter, the store-activated endoplasmic reticulum Ca++ sensor, these may represent post-translationally modified ORAI 3, ORAI3 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels |
| Gene names | ORAI3 Antibody [2H2G9] : TMEM142C |
| Antibodie's label | unlabelled serum |
| Purity | ORAI3 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 2H2G9 |
| Immunoglobulin | IgG2a |
| Antigen | A 19 amino acid synthetic peptide from near the carboxy terminus of human ORAI3 |
| Immuno application | Western Blot, immuno fluorescence, immuno-histo-chemistry, ELISA |
| Antibody advice | Antibody can also be used for immunohistochemistry starting at 2, For immunofluorescence start at 5 ug/mL, 5 ug/mL, ORAI3 antibody can be used for detection of ORAI3 by Western blot at 2 ug/mL |
| Suspention, pH, azide | 02% sodium azide, ORAI3 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for one year, ORAI3 monoclonal antibody can be stored at -20 grades C |
| Works with | Rat, Human |
| Omim nr | 74732916 |
| Ncbi nr | Q9BRQ5 |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 93129 |
| GENE symbol | ORAI3 |
| Antigene name | ORAI calcium release-activated calcium modulator 3 |
| Source | homo sapiens |
| Protein nr | Q9BRQ5 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | ORAI3 [2H2G9] |
| Short name | anti-ORAI3 Antibody [2H2G9] |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-ORAI3 (Antibody to) [2H2G9] |
| Alternative technique | antibodies |
| Identity | 3829 |
| Gene | FRA10A |
| Long gene name | folic acid type, fra(10)(q23, fragile site, rare, 2) , 3) or fra(10)(q24 |
| Locus | 10q23, 2 , 3 or 10q24 |
| Discovery year | 1986-01-01 |
| Pubmed identfication | 15203205 |