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Anti-OSBP2 (Polyclonal), ALEXA Fluor 594

Anti-OSBP2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOSBP2
SpecificityThis antibody reacts specifically with OSBP2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human OSBP2
Gene ID23762
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information HMG-CoA reductase and the low density lipoprotein receptor (LDLR), OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), OSBP localizes to the cytosol and is widely expressed, OSBPs are involved in lipid metabolism and signal transduction, The OSBP protein transports sterols from lysosomes to the nucleus, The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties, a suppressor of cholesterol synthesis gene transcription in cultured cells, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols, as well as vesicle transport, retina and fetal liver, where sterols downregulate the genes for HMG synthetase, which share a high overall similarity, while OSBP2 is mainly detected in testis, The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1664 ORP-4 ORP4
Also known asOSBP2 Polyclonal Antibody
Other nameAnti-OSBP2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOSBP2
Short nameAnti-OSBP2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-OSBP2 (polyclonal)
Alternative techniquepolyclonals
Identity 8504
Gene OSBP2
Long gene name oxysterol binding protein 2
Synonyms gene OSBPL1
Locus 22q12, 2
Discovery year 1999-10-29
Entrez gene record 23762
Pubmed identfication 10591208 11278871 11802775
RefSeq identity NM_030758
Classification Pleckstrin homology domain containing Oxysterol binding proteins
Havana BLAST/BLAT OTTHUMG00000151153

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