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Anti-OST-beta (Polyclonal), ALEXA Fluor 594

Anti-OST-beta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOST-beta
SpecificityThis antibody reacts specifically with OST-beta
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human OST-beta
Gene ID123264
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms OST KIAA0115 OST48 WBP1
Also known asOST-beta Polyclonal Antibody
Other nameAnti-OST-beta Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOST-beta
Short nameAnti-OST-beta (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-OST-b (polyclonal)
Alternative techniquepolyclonals
Identity 2728
Gene DDOST
Long gene name dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Synonyms gene name dolichyl-diphosphooligosaccharide-protein glycosyltransferase
Synonyms name oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1
Locus 1p36, 12
Discovery year 1997-12-23
GenBank acession D29643
Entrez gene record 1650
Pubmed identfication 9367678
RefSeq identity NM_005216
Classification Oligosaccharyltransferase complex subunits
Havana BLAST/BLAT OTTHUMG00000002844

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