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Anti-OTP (Polyclonal), ALEXA Fluor 594

Anti-OTP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideOTP
SpecificityThis antibody reacts specifically with OTP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human OTP
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information At early embryonic stages in mice, Containing a homeobox DNA-binding domain and a OAR domain, OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily, OTP is expressed in neurons, OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells, anterior periventricular (aPV) and arcuate (ARN) nuclei, indicating a potential role for OTP as an upstream regulator of SIM2, supraoptic (SON), the expression of SIM2 is downregulated in the absence of OTP, which contains 181 million base pairs and comprises nearly 6% of the human genome, which give rise to the paraventricular (PVN), Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asOTP Polyclonal Antibody
Other nameAnti-OTP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetOTP
Short nameAnti-OTP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-OTP (polyclonal)
Alternative techniquepolyclonals
Identity 8518
Gene OTP
Long gene name orthopedia homeobox
Synonyms gene name orthopedia homolog (Drosophila)
Locus 5q14, 1
Discovery year 1999-02-09
Entrez gene record 23440
Pubmed identfication 10458915
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000102171

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