Name : Anti-P2Y10 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4672620583
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | P2Y10 |
| Specificity | This antibody reacts specifically with P2Y10 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human P2Y10 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 10), G-protein coupled, P2Y10 (purinergic receptor P2Y, P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation, The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, To some extent, also known as P2RY10, alternatively, chemotaxis and cytokine release, designated P2X and P2Y, differentiation, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins, primarily through the activation of phospholipase C (PLC), such as cell proliferation, the P2Y receptors can also activate potassium channels or, Nucleotides are important extracellular signaling molecules that mediate several events |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | P2Y10 |
| Also known as | P2Y10 Polyclonal Antibody |
| Other name | Anti-P2Y10 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | P2Y10 |
| Short name | Anti-P2Y10 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-P2Y10 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 19906 |
| Gene | P2RY10 |
| Long gene name | purinergic receptor P2Y10 |
| Synonyms gene name | 10 , G-protein coupled, purinergic receptor P2Y |
| Locus | Xq21, 1 |
| Discovery year | 2003-01-28 |
| GenBank acession | AF000545 |
| Pubmed identfication | 11004484 9755289 |
| Classification | Purinergic receptors P2Y |
| Havana BLAST/BLAT | OTTHUMG00000021896 |
| Locus Specific Databases | Mental Retardation database |