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Anti-P2Y6 (Polyclonal), ALEXA Fluor 594

Anti-P2Y6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideP2Y6
SpecificityThis antibody reacts specifically with P2Y6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human P2Y6
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information However, P2X and P2Y, The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP, The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, The P2Y receptors are differentially expressed in several tissue types, To some extent, all P2Y receptors are expressed in leukocytes, alternatively, chemotaxis and cytokine release, differentiation, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides, lung and brain, primarily through the activation of phospholipase C, such as heart, such as proliferation, the P2Y receptors can also activate potassium channels or, which suggests a role for the P2Y receptor family in the activation of leukocytes and platelets in response to inflammation or vascular damage, Nucleotides are emerging as important extracellular signaling molecules that mediate several effects
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms P2Y6
Also known asP2Y6 Polyclonal Antibody
Other nameAnti-P2Y6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetP2Y6
Short nameAnti-P2Y6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-P2Y6 (polyclonal)
Alternative techniquepolyclonals
Identity 8543
Gene P2RY6
Long gene name pyrimidinergic receptor P2Y6
Synonyms gene name 6 , G-protein coupled, pyrimidinergic receptor P2Y
Locus 11q13, 4
Discovery year 1997-01-16
Entrez gene record 5031
Pubmed identfication 8670200
Classification Purinergic receptors P2Y
Havana BLAST/BLAT OTTHUMG00000167969

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