Name : anti-p53 (phospho Ser392) Antibody
Supplier : PROSCIENCE
Price :180
SKU : GEN9291513610
| Gene info | An increase in p53 has also been linked to deficits in LTP and learning and memory, In addition p53 has also been linked to affects of aging and oxidative stress, It has been called the guardian of the genome, Phosphorylation of Ser392 in p53 is associated with formation of human tumors, We raised this polyclonal antibody against a peptide representing the sequence around Ser392 of p53, p53 has a well established role in the blocking the proliferative action of damaged cells and acting in essence as an anticancer agent |
| Gene names | Antigen NY-CO-13, BCC7, LFS1, P53, TRP53, P53 |
| Antibodie's label | unlabelled serum |
| Purity | Affinity Purified |
| Ab raised in | Rabbit |
| Type | Polyclonal |
| Spicific to | p53 antibody is specific for the 53 kDa p53 protein phosphorylated at Ser392 |
| Antigen | p53 (Ser392) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser392 of p53 |
| Immuno application | Western Blot |
| Antibody advice | Applications include Dot Blots (DB) and Western Blots (WB), Human and some non-human primates have 100% amino acid sequence identity with the antigen used to raise the antibody, Immunohistochemistry: not determined, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, Immunolabeling of the 53 kDa p53 protein in Western blots of PMA treated NIH3T3 cells is blocked by the Ser392 phosphopeptide used as antigen but by the corresponding non-phosphopeptide |
| Suspention, pH, azide | 100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5) |
| Keep at | Stable for one year, but shorter term storage at &ndash, 20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, 80 grades C is recommended, For long term storage &ndash |
| Works with | Monkey, Human |
| Omim nr | 269849759 |
| Ncbi nr | P04637 |
| KDa | 53 |
| Vial with antibody | in solution |
| NCBI GENE nr | 7157 |
| GENE symbol | TP53 |
| Antigene name | tumor protein p53 |
| Source | Homo sapiens |
| Protein nr | P04637 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | p53 (phospho Ser392) |
| Short name | anti-p53 (phospho Ser392) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-p53 (phosphorilated Ser392) (Antibody to) |
| Alternative technique | antibodies |