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Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594

Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594 size: 143 microliters 489

Supplier BIOSS MONOCLONAL ANTIBODIES
Price 489
Size 143 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated withALEXA FLUOR 594
Host organismMouse (Mus musculus)
Target Protein/PeptideP53wt-p53
SpecificityHighly specific antibody against P53wt-p53
ModificationNot modified
ClonalityMonoclonal Antibodies
CloneD2F7
Concentration1ug per 1ul
Antigen SourceKLH conjugated synthetic peptide derived from human P53(wt-p53)
Gene ID7157
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross Reactive species Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species detailsNo significant cross reactivity is observed
Background information 20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation
Purification methodPurified by Protein G
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months
Excitation emission590nm/617nm
Synonyms p53 LFS1
Alternative name 1 594 Conjugated, ALEXA FLUOR®, P53(wt-p53) (D2F7) Monoclonal Antibody
Alternative name 2 ALEXA FLUOR 594 Conjugated, P53(wt-p53) (D2F7) Monoclonal anti-
Advisory For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetP53(wt-p53) (D2F7) Monoclonal
Short name Fluor 594, Anti-P53(wt-p53) (D2F7) Monoclonal
TechniqueMonoclonals or monoclonal antibodies
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-P53(wt-p53) (D2F7) monoclonal
Identity 11998
Gene TP53
Long gene name tumor protein p53
Synonyms name Li-Fraumeni syndrome
Locus 17p13, 1
Discovery year 1986-01-01
GenBank acession AF307851
Entrez gene record 7157
Pubmed identfication 6396087 3456488 2047879
RefSeq identity NM_000546
Havana BLAST/BLAT OTTHUMG00000162125
Locus Specific Databases IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321

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