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Anti-PABP (Methyl Arg455/460), ALEXA Fluor 594

Anti-PABP (Methyl Arg455/460), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePABP Methyl Arg455/460
SpecificityThis antibody reacts specifically with PABP (Methyl Arg455/460)
ModificationMethylation
Modification siteMethyl Arg455/460
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic metylpeptide derived from human PABP around metylation site of Arg455/Arg460
Gene ID26986
Swiss ProtP11940
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo, Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain, Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons, Involved in translationally coupled mRNA turnover, Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2, May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing, for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed, including that of its own transcript, Binds the poly(A) tail of mRNA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PABP, PABP-1, PABP1, PABPC1, PABPC2, PABPL1, Poly(A)-binding protein 1, Polyadenylate-binding protein 1, PAB1
Also known asPABP (Methyl Arg455/460) Antibody
Other nameAnti-PABP (Methyl Arg455/460)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description All three forms are highly reactive and rarely observed, CH3, In , It is a very stable group in most molecules, Such hydrocarbon , The anion has eight valence electrons, While the methyl group is usually part of a larger , containing one , it can be found on its own in any of three forms , the group is often , the radical seven and the cation six,  , A , Me, abbreviated , alkyl , anion, atom , atoms &mdash, bonded , carbon , cation , derived from , formulas, groups occur in many , hydrogen , is an , methane, methyl group , molecule, or , organic compounds, radical, to three 
Gene targetPABP (Methyl Arg455/460)
Short nameAnti-PABP (Methyl Arg455/460) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PABP (Methyl Arg455/460)

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