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Anti-PAG1 (Polyclonal), ALEXA Fluor 594

Anti-PAG1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePAG1
SpecificityThis antibody reacts specifically with PAG1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PAG1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Cbp is a component of the regulatory mechanism controlling the activity of membrane-associated Src-PTKs, Cbp is exclusively localized in the GM1 ganglioside-enriched detergent-insoluble membrane domain, Cbp is involved in the membrane localization of Csk and in Csk-mediated inhibition of c-Src, Csk binding protein (Cbp), In the plasma membrane, The activity of Src-PTKs in cells of different types is negatively controlled by Csk, also designated phosphoprotein associated with glycosphingo-lipid-enriched microdomains (GEMs) or PAG, is a ubiquitously expressed transmembrane phosphoprotein that binds specifically to the SH2 domain of Csk, which is important in receptor-mediated signaling, The Src family of protein tyrosine kinases (Src-PTKs) is important in the regulation of growth and differentiation of eukaryotic cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PAG CBP
Also known asPAG1 Polyclonal Antibody
Other nameAnti-PAG1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPAG1
Short nameAnti-PAG1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-phosphoprotein associated with glycosphin this GO lipid microdomains 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target PAG1 and IDBG-26542 and ENSG00000076641 and 55824, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, Plasma membranes, SH2 domain binding, this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0045121 and membrane raft and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0042169: SH2 domain binding, this GO :0005515: protein binding, this GO :0042169: SH2 domain binding, phosphoprotein associated with glycosphin this GO lipid microdomains 1
Identity 30043
Gene PAG1
Long gene name phosphoprotein membrane anchor with glycosphingolipid microdomains 1
Synonyms gene name phosphoprotein associated with glycosphingolipid microdomains 1
Synonyms name Csk-binding protein transmembrane adaptor protein PAG
Locus 8q21, 13
Discovery year 2005-04-25
GenBank acession AF240634
Entrez gene record 55824
Pubmed identfication 10790433
RefSeq identity NM_018440
Havana BLAST/BLAT OTTHUMG00000164592

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