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Anti-PAI-2/SerpinB2 (Polyclonal), ALEXA Fluor 594

Anti-PAI-2/SerpinB2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePAI-2/SerpinB2
SpecificityThis antibody reacts specifically with PAI-2/SerpinB2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PAI-2
Gene ID5055
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It was first discovered in the placenta, SerpinB2 also inhibits tissue plasminogen activator (t-PA), SerpinB2 is found in saliva, SerpinB2 is made by many cell types, SerpinB2 levels are elevated in serum during pregnancy, The shorter form has a deletion just after the start of the mature protein, The structure of PAI-2 is not terribly similar to PAI-1, although it was lowered in some cancers, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency, and in leukemia, and in the skin, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein, breast cancer and ovarian cancer, but it is unclear what the relative production and distribution is for the shorter sequence, but with micromolar efficiency, has been reported, however, secreted by gingival fibroblasts, which is an E clade serpin, with a predicted mass of 43, 1 kDa and a pI of 5, 69, A shorter SerpinB2 isoform of 382 amino acids, SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HsT1201, Monocyte Arg serpin, Monocyte Arg-serpin, PAI, PAI 2, PAI-2, PAI2, PAI2A, PAI2_RAT, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Plasminogen activator inhibitor 2 type A, Serpin peptidase inhibitor clade B ovalbumin member 2, SerpinB2, Serpinb2, Urokinase inhibitor, plasminogen activator inhibitor 2, Serpin B2
Also known asPAI-2/SerpinB2 Polyclonal Antibody
Other nameAnti-PAI-2/SerpinB2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPAI-2/SerpinB2
Short nameAnti-PAI-2/SerpinB2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, clade B (ovalbumin), member 2 (polyclonal), antibody to-PAI-2/serpin peptidase inhibitor
Alternative techniquepolyclonals

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