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Anti-PAK6 (Polyclonal), ALEXA Fluor 594

Anti-PAK6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePAK6
SpecificityThis antibody reacts specifically with PAK6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PAK6
Gene ID56924
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information PAK kinases are implicated in the regulation of a number of cellular processes, The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen, The protein encoded by this gene was found to interact with androgen receptor (AR), The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, apoptosis and the MAP kinase signaling pathway, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain, including cytoskeleton rearrangement, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PAK5
Also known asPAK6 Polyclonal Antibody
Other nameAnti-PAK6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPAK6
Short nameAnti-PAK6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PAK6 (polyclonal)
Alternative techniquepolyclonals
Identity 16061
Gene PAK6
Long gene name p21 (RAC1) activated kinase 6
Synonyms gene name p21(CDKN1A)-activated kinase 6 p21 protein (Cdc42/Rac)-activated kinase 6
Locus 15q15, 1
Discovery year 2001-07-12
GenBank acession AF276893
Entrez gene record 56924
Pubmed identfication 11278661
Havana BLAST/BLAT OTTHUMG00000129921

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