Name : Anti-Pantophysin (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5068115831
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Pantophysin |
| Specificity | This antibody reacts specifically with Pantophysin |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Pantophysin |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Citrullinemia and Shwachman-Diamond syndrome, Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Expressed as multiple alternatively spliced isoforms, Lissencephaly, MARVEL domain-containing proteins are thought to participate in tight junction regulation, Pantophysin, Pendred syndrome, The gene encoding pantophysin maps to human chromosome 7, Williams-Beuren syndrome, also known as SYPL1 (synaptophysin-like protein 1) or H-SP1, and contains one MARVEL domain, as well as to the cytoplasm, both of which have cytoplasmic N- and C-terminal regions, is a 259 amino acid multi-pass membrane protein that localizes to melanosomes and vesicles, pantophysin is present in tissues throughout the body where it may play a role in vesicle trafficking and protein transport, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events, which houses over 1, 000 genes and comprises nearly 5% of the human genome, The MARVEL domain is a 130 amino acid motif that contains four transmembrane helices |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | H-SP1, Pantophysin, SYPL, SYPL1, Synaptophysin-like protein 1, SYPL1_HUMAN |
| Also known as | Pantophysin Polyclonal Antibody |
| Other name | Anti-Pantophysin Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Pantophysin |
| Short name | Anti-Pantophysin (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Pantophysin (polyclonal) |
| Alternative technique | polyclonals |