Anti-PARP3 (Polyclonal), ALEXA Fluor 594

Anti-PARP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	PARP3
Specificity	This antibody reacts specifically with PARP3
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human PARP3
Gene ID	10039
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Binds DNA, May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing, May link the DNA damage surveillance network to the mitotic fidelity checkpoint, Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication, This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks, also detected in pancreas, brain, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, colon, heart and spleen, leukocytes, liver, lung, ovary, placenta, prostate and thymus, skeletal muscle, small intestine, testis, the highest levels are in the kidney, Involved in the base excision repair (BER) pathway, Tissue specificity: Widely expressed
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	ADPRT3 IRT1 hPARP-3 pADPRT-3
Also known as	PARP3 Polyclonal Antibody
Other name	Anti-PARP3 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	PARP3
Short name	Anti-PARP3 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-PARP3 (polyclonal)
Alternative technique	polyclonals
Identity	273
Gene	PARP3
Long gene name	poly(ADP-ribose) polymerase family member 3
Synonyms gene	ADPRTL3
Synonyms gene name	ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3
Synonyms name	poly(ADP-ribose) synthetase-3 NAD+ ADP-ribosyltransferase 3 poly(ADP-ribose) polymerase 3
Locus	3p21, 2
Discovery year	1999-05-24
GenBank acession	AF083068
Entrez gene record	10039
Pubmed identfication	10329013
RefSeq identity	NM_005485, 4
Classification	Poly(ADP-ribose) polymerases
Havana BLAST/BLAT	OTTHUMG00000156931

Anti-PARP3 (Polyclonal), ALEXA Fluor 594

Anti-PARP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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