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Anti-PATJ (Polyclonal), ALEXA Fluor 594

Anti-PATJ (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePATJ
SpecificityThis antibody reacts specifically with PATJ
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PATJ
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), PATJ associates with Claudin-1, Pals-associated tight junction protein (PATJ), The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity, Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes, all of which are found in regions of noncompact myelin: the paranodal loops, and Pals1 (a Lin-7 associated protein), gap and adherens junctions, incisures of Schmidt-Lanterman and mesaxons, is differentially localized in myelinating Schwann cells, the human homolog of Drosophila Discs Lost, The membranes of myelinating Schwann cells are joined by tight
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Cipp
Also known asPATJ Polyclonal Antibody
Other nameAnti-PATJ Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPATJ
Short nameAnti-PATJ (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PATJ (polyclonal)
Alternative techniquepolyclonals
Identity 28881
Gene PATJ
Long gene name PATJ, crumbs cell polarity complex component
Synonyms gene INADL
Synonyms gene name InaD-like (Drosophila)
Synonyms name inactivation-no-afterpotential D-like Pals1-associated tight junction
Locus 1p31, 3
Discovery year 2004-12-23
GenBank acession AB044807
Entrez gene record 10207
Pubmed identfication 9280290 11374908
RefSeq identity NM_170605
Classification Crumbs complex PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000008560

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