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Anti-PCDHB11 (Polyclonal), ALEXA Fluor 594

Anti-PCDHB11 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePCDHB11
SpecificityThis antibody reacts specifically with PCDHB11
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PCDHB11
Gene ID56125
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters, The beta cluster contains 16 genes and 3 pseudogenes, The extracellular domains interact in a homophilic manner to specify differential cell-cell connections, Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections, These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins, Unlike the alpha and gamma clusters, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily, not sharing common 3' exons as expected, one of three related gene clusters tandemly linked on chromosome five, the transcripts from these genes are made up of only one large exon, PCDHB11 is a member of the protocadherin beta gene cluster
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PCDH-BETA11 ME2
Also known asPCDHB11 Polyclonal Antibody
Other nameAnti-PCDHB11 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPCDHB11
Short nameAnti-PCDHB11 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-protocadherin b 11 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target PCDHB11 and IDBG-50113 and ENSG00000197479 and 56125, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 11
Identity 8682
Gene PCDHB11
Long gene name protocadherin beta 11
Synonyms name cadherin ME2
Locus 5q31, 3
Discovery year 2000-06-28
GenBank acession AF152490
Entrez gene record 56125
Pubmed identfication 10380929
RefSeq identity NM_018931
Classification Clustered protocadherins
Havana BLAST/BLAT OTTHUMG00000129618

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