Name : Anti-PCDHGB5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1839648067
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PCDHGB5 |
| Specificity | This antibody reacts specifically with PCDHGB5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human PCDHGB5 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alternative splicing has been described for the gamma cluster genes, Each variable region exon encodes the extracellular region, Subfamily A contains 12 genes, The constant region exons encode the common cytoplasmic region, The gamma gene cluster includes 22 genes divided into 3 subfamilies, The tandem array of 22 large, These gene clusters have an immunoglobulin-like organization, These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain, and the more distantly related subfamily C contains 3 genes, containing 3 exons shared by all genes in the cluster, one of three related clusters tandemly linked on chromosome five, subfamily B contains 7 genes and 2 pseudogenes, suggesting that a novel mechanism may be involved in their regulation and expression, variable region exons are followed by a constant region, which includes 6 cadherin ectodomains and a transmembrane region, PCDHGB5 is a member of the protocadherin gamma gene cluster |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PCDH-GAMMA-B5 |
| Also known as | PCDHGB5 Polyclonal Antibody |
| Other name | Anti-PCDHGB5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PCDHGB5 |
| Short name | Anti-PCDHGB5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-PCDHGB5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 8712 |
| Gene | PCDHGB5 |
| Long gene name | 5 , protocadherin gamma subfamily B |
| Locus | 5q31 |
| Discovery year | 2000-06-28 |
| GenBank acession | AF152521 |
| Entrez gene record | 56101 |
| Pubmed identfication | 10380929 |
| RefSeq identity | NM_018925 |
| Classification | Clustered protocadherins |
| Havana BLAST/BLAT | OTTHUMG00000188231 |