Name : anti-PD-1 Antibody [7A11B1]
Supplier : PROSCIENCE
Price :180
SKU : GEN9249036116
| Gene info | Despite its predicted molecular weight, Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases, PD-1 can bind two different but related ligands, PD-1 often migrates at higher molecular weight in SDS-PAGE, PDL-1 and PDL-2, T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC, Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ", such as LPS or other molecules associated with bacteria or other pathogens, PD-1 Monoclonal Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC), danger signals" |
| Gene names | CD279, PD-1, SLEB2, hPD-1, hPD-l, hSLE1, PD-1 Antibody [7A11B1] : PD1 |
| Antibodie's label | unlabelled serum |
| Purity | PD-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 7A11B1 |
| Immunoglobulin | IgG1 |
| Antigen | A ~150 amino acid recombinant protein from near the amino terminus of mouse PD-1 |
| Immuno application | Western Blot, immuno fluorescence, immuno-histo-chemistry, ELISA |
| Antibody advice | Antibody can also be used for immunohistochemistry starting at 2, For immunofluorescence start at 20 ug/mL, 5 ug/mL, PD-1 antibody can be used for detection of PD-1 by Western blot at 1 ug/mL |
| Suspention, pH, azide | 02% sodium azide, PD-1 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for one year, PD-1 monoclonal antibody can be stored at -20 grades C |
| Works with | Mouse, Rat, Human |
| Omim nr | 148707975 |
| Ncbi nr | EDL39922 |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 5133 |
| GENE symbol | PDCD1 |
| Antigene name | programmed cell death 1 |
| Source | mus musculus |
| Protein nr | Q15116 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | PD-1 [7A11B1] |
| Short name | anti-PD-1 Antibody [7A11B1] |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-PD-1 (Antibody to) [7A11B1] |
| Alternative technique | antibodies |
| Identity | 8760 |
| Gene | PDCD1 |
| Long gene name | programmed cell death 1 |
| Synonyms gene | SLEB2 |
| Synonyms gene name | systemic lupus erythematosus susceptibility 2 |
| Synonyms | CD279 PD1 hSLE1 PD-1 |
| Locus | 2q37, 3 |
| Discovery year | 1994-05-24 |
| GenBank acession | AY206416 |
| Entrez gene record | 5133 |
| Pubmed identfication | 7851902 12402038 |
| RefSeq identity | NM_005018 |
| Classification | CD molecules V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000151342 |