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anti-PD-1 Antibody [7A11B1]

anti-PD-1 Antibody [7A11B1] size: 0.02 mg, 0.1 mg 180

Supplier PROSCIENCE
Price 180
Size 0.02 mg, 0.1 mg
Gene info Despite its predicted molecular weight, Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases, PD-1 can bind two different but related ligands, PD-1 often migrates at higher molecular weight in SDS-PAGE, PDL-1 and PDL-2, T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC, Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ", such as LPS or other molecules associated with bacteria or other pathogens, PD-1 Monoclonal Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC), danger signals"
Gene names CD279, PD-1, SLEB2, hPD-1, hPD-l, hSLE1, PD-1 Antibody [7A11B1] : PD1
Antibodie's labelunlabelled serum
PurityPD-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG
Ab raised inMouse
TypeMonoclonal
Monoclonal7A11B1
ImmunoglobulinIgG1
AntigenA ~150 amino acid recombinant protein from near the amino terminus of mouse PD-1
Immuno application Western Blot, immuno fluorescence, immuno-histo-chemistry, ELISA
Antibody advice Antibody can also be used for immunohistochemistry starting at 2, For immunofluorescence start at 20 ug/mL, 5 ug/mL, PD-1 antibody can be used for detection of PD-1 by Western blot at 1 ug/mL
Suspention, pH, azide02% sodium azide, PD-1 Monoclonal Antibody is supplied in PBS containing 0
Keep at stable for one year, PD-1 monoclonal antibody can be stored at -20 grades C
Works with Mouse, Rat, Human
Omim nr148707975
Ncbi nrEDL39922
Vial with antibodyin solution
Quantity per ml1 mg/mL
NCBI GENE nr5133
GENE symbolPDCD1
Antigene nameprogrammed cell death 1
Sourcemus musculus
Protein nrQ15116
Description Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4°
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24°
Gene targetPD-1 [7A11B1]
Short nameanti-PD-1 Antibody [7A11B1]
Technique antibodies against human proteins, antibodies for, antibody to, Antibody
Alternative nameantibody to-PD-1 (Antibody to) [7A11B1]
Alternative techniqueantibodies
Identity 8760
Gene PDCD1
Long gene name programmed cell death 1
Synonyms gene SLEB2
Synonyms gene name systemic lupus erythematosus susceptibility 2
Synonyms CD279 PD1 hSLE1 PD-1
Locus 2q37, 3
Discovery year 1994-05-24
GenBank acession AY206416
Entrez gene record 5133
Pubmed identfication 7851902 12402038
RefSeq identity NM_005018
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000151342

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