Name : Anti-PDCD10 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3518401643
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PDCD10 |
| Specificity | This antibody reacts specifically with PDCD10 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cell membrane, Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human PDCD10 |
| Gene ID | 11235 |
| Swiss Prot | Q9BUL8 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Important for KDR/VEGFR2 signaling, Important for cell migration, Increases mitogen-activated protein kinase activity and STK26 activity, Increases the stability of KDR/VEGFR2 and prevents its breakdown, Modulates apoptotic pathways, Required for normal angiogenesis, Required for normal cardiovascular development, and for normal structure and assembly of the Golgi complex, vasculogenesis and hematopoiesis during embryonic development (By similarity), Promotes cell proliferation |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | TFAR15 |
| Also known as | PDCD10 Polyclonal Antibody |
| Other name | Anti-PDCD10 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PDCD10 |
| Short name | Anti-PDCD10 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-programmed cellular death 10 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CCM3 and TFAR15, PDCD10 and IDBG-636835 and ENSBTAG00000031709 and 506411, PDCD10 and IDBG-64018 and ENSG00000114209 and 11235, Pdcd10 and IDBG-152450 and ENSMUSG00000027835 and 56426, Plasma membranes, protein N-terminus binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001525 and angiogenesis and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0047485: protein N-terminus binding, this GO :0042803: protein homodimerization activity, this GO :0047485: protein N-terminus binding, 785119, programmed cell death 10 |
| Identity | 8761 |
| Gene | PDCD10 |
| Long gene name | programmed cell death 10 |
| Synonyms gene | CCM3 |
| Synonyms gene name | cerebral cavernous malformations 3 |
| Locus | 3q26, 1 |
| Discovery year | 1999-12-10 |
| GenBank acession | AF022385 |
| Entrez gene record | 11235 |
| Pubmed identfication | 15543491 |
| RefSeq identity | NM_007217 |
| Classification | STRIPAK complex |
| Havana BLAST/BLAT | OTTHUMG00000158415 |
| Locus Specific Databases | LRG_651 |