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Anti-PDE4D (Polyclonal), ALEXA Fluor 594

Anti-PDE4D (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePDE4D
SpecificityThis antibody reacts specifically with PDE4D
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PDE4D
Gene ID5144
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information D2, D3, D4 and D5), In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities, One or more PDE4D subtype variants are ubiquitously present in all mammalian cells, Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins, PDE4D1/D2 mRNA levels rise in response to an increase in cAMP, Peripheral tissues also exhibit differential expression of PDE4D variants, Short term regulation of PDE4D variants involved PKA, Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asPDE4D Polyclonal Antibody
Other nameAnti-PDE4D Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPDE4D
Short nameAnti-PDE4D (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PDE4D (polyclonal)
Alternative techniquepolyclonals
Identity 8783
Gene PDE4D
Long gene name phosphodiesterase 4D
Synonyms gene DPDE3
Synonyms gene name cAMP-specific , cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) phosphodiesterase 4D, phosphodiesterase 4D
Synonyms name phosphodiesterase E3 dunce homolog (Drosophila)
Locus 5q11, 1 , 2-q12
Discovery year 1992-06-08
Entrez gene record 5144
Classification Phosphodiesterases
Havana BLAST/BLAT OTTHUMG00000162218

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