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Anti-PDHA1 (Polyclonal), ALEXA Fluor 594

Anti-PDHA1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePDHA1
SpecificityThis antibody reacts specifically with PDHA1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsMitochondrion
Antigen SourceKLH conjugated synthetic peptide derived from human PDHA1
Gene ID5160
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternatively spliced transcript variants encoding different isoforms have been found for this gene, Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome, The E1 enzyme is a heterotetramer of two alpha and two beta subunits, The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3), The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asPDHA1 Polyclonal Antibody
Other nameAnti-PDHA1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPDHA1
Short nameAnti-PDHA1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PDHA1 (polyclonal)
Alternative techniquepolyclonals
Identity 8806
Gene PDHA1
Long gene name pyruvate dehydrogenase (lipoamide) alpha 1
Synonyms gene PDHA
Synonyms name mitochondrial , pyruvate dehydrogenase E1 component subunit alpha, somatic form
Locus Xp22, 12
Discovery year 1989-06-30
Entrez gene record 5160
Havana BLAST/BLAT OTTHUMG00000021224
Locus Specific Databases Mental Retardation database

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