Anti-PDPK1(Tyr9) (Polyclonal), ALEXA Fluor 594

Anti-PDPK1(Tyr9) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	PDPK1 Tyr9
Specificity	This antibody reacts specifically with PDPK1(Tyr9)
Modification	Phosphorylation
Modification site	Tyr9
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus, Cytoplasm
Antigen Source	KLH conjugated synthetic phosphopeptide derived from human PDK1 around the phosphorylation site of Tyr9
Gene ID	5170
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Activates PPARG transcriptional activity and promotes adipocyte differentiation, Activates the NF-kappa-B pathway via phosphorylation of IKKB, Controls proliferation, Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis, Its targets include: protein kinase B (PKB/AKT1, Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, PKB/AKT2, PKB/AKT3), Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells, Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response, RPS6KA2 and RPS6KA3), SGK2 and SGK3), SMAD3, SMAD4 and SMAD7, The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II, and growth of developing pancreatic cells, as well as glucose and amino acid uptake and storage, cyclic AMP-dependent protein kinase (PRKACA), p21-activated kinase-1 (PAK1), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, phosphorylating SMAD2, phosphorylating and activating a subgroup of the AGC family of protein kinases, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta, protein kinase C (PRKCD and PRKCZ), protein kinase PKN (PKN1 and PKN2), serum and glucocorticoid-inducible kinase (SGK1, survival, thus propagating the signal to downstream targets controlling cell proliferation and survival, Serine/threonine kinase which acts as a master kinase
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	PDK1
Also known as	PDPK1(Tyr9) Polyclonal Antibody
Other name	Anti-PDPK1(Tyr9) Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	PDPK1(Tyr9)
Short name	Anti-PDPK1(Tyr9) (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-PDPK1(Tyr9) (polyclonal)
Alternative technique	polyclonals
Identity	8816
Gene	PDPK1
Long gene name	3-phosphoinositide dependent protein kinase 1
Synonyms name	PkB kinase
Locus	16p13, 3
Discovery year	1998-03-23
GenBank acession	AF017995
Entrez gene record	5170
Pubmed identfication	9094314 9445477
Havana BLAST/BLAT	OTTHUMG00000128874

Anti-PDPK1(Tyr9) (Polyclonal), ALEXA Fluor 594

Anti-PDPK1(Tyr9) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

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