Name : Anti-PEA15 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8375288187
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PEA15 |
| Specificity | This antibody reacts specifically with PEA15 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human PEA15 |
| Gene ID | 8682 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function, and a C terminal region containing two serine phosphorylation sites, and insulin sensitive glucose transport in insulin responsive cells, integrin activation, PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | HMAT1 MAT1 PED PEA-15 MAT1H HUMMAT1H |
| Also known as | PEA15 Polyclonal Antibody |
| Other name | Anti-PEA15 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PEA15 |
| Short name | Anti-PEA15 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-phosphoprotein enriched in astrocytes 15 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | Cytoplasm, HMAT1 and HUMMAT1H and MAT1 and MAT1H and PEA-15 and PED, PEA15 and IDBG-104008 and ENSG00000162734 and 8682, PEA15 and IDBG-630628 and ENSBTAG00000005793 and 510586, Pea15a and IDBG-205249 and ENSMUSG00000013698 and 18611, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005875 and microtubule associated complex and cellular component this GO :0006810 and transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0008643 and carbohydrate transport and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043278 and response to morphine and biological process this GO :0046325 and negative regulation of glucose import and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, phosphoprotein enriched in astrocytes 15 |
| Identity | 8822 |
| Gene | PEA15 |
| Long gene name | phosphoprotein enriched in astrocytes 15 |
| Synonyms name | 15kD homolog of mouse MAT-1 oncogene , Phosphoprotein enriched in astrocytes |
| Locus | 1q23, 2 |
| Discovery year | 1998-11-06 |
| GenBank acession | Y13736 |
| Entrez gene record | 8682 |
| Pubmed identfication | 9205133 |
| RefSeq identity | NM_003768 |
| Classification | Death effector domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031605 |