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Anti-PERK(Thr980) (Polyclonal), ALEXA Fluor 594

Anti-PERK(Thr980) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePERK Thr980
SpecificityThis antibody reacts specifically with PERK(Thr980)
ModificationPhosphorylation
Modification siteThr980
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from mouse PERK around the phosphorylation site of Thr981
Gene ID13666
Swiss ProtQ9Z2B5
Applications IF(ICC), IF(IHC-P)
Applications with corresponding dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Involved in control of mitochondrial morphology and function, Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis, Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PEK PERK
Also known asPERK(Thr980) Polyclonal Antibody
Other nameAnti-PERK(Thr980) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPERK(Thr980)
Short nameAnti-PERK(Thr980) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PERK(Thr980) (polyclonal)
Alternative techniquepolyclonals
Identity 3255
Gene EIF2AK3
Long gene name eukaryotic translation initiation factor 2 alpha kinase 3
Locus 2p11, 2
Discovery year 1999-06-14
GenBank acession AF110146
Entrez gene record 9451
Pubmed identfication 10026192 10575235
RefSeq identity NM_004836
Havana BLAST/BLAT OTTHUMG00000155046
Locus Specific Databases LRG_1024

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