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Anti-PFK2 (Ser467) (Polyclonal), ALEXA Fluor 594

Anti-PFK2 (Ser467) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePFK2 Ser467
SpecificityPFK2 (Ser467), This phosphorylated site is homologous to that of Ser467 in Mouse and Ser496 in Rat
ModificationPhosphorylation
Modification siteSer467
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467
Gene ID5209
Swiss ProtQ16875
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Fructose-2, Glycolytic flux is key to tumour growth, Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth, which catalyses a key step in the glycoytic pathway, 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2, 6-bisphosphate, 6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6PF-2-K/Fru-2, IPFK2, PFK/FBPase 3, PFKFB3, Renal carcinoma antigen NY-REN-56, iPFK-2, 6-P2ase 3, 6-P2ase brain/placenta-type isozyme, 6-bisphosphatase 3, PFK2
Also known asPFK2 (Ser467) Polyclonal Antibody
Other nameAnti-PFK2 (Ser467) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPFK2 (Ser467)
Short nameAnti-PFK2 (Ser467) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PFK2 (Ser467) (polyclonal)
Alternative techniquepolyclonals

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