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Anti-PGCP (Polyclonal), ALEXA Fluor 594

Anti-PGCP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePGCP
SpecificityThis antibody reacts specifically with PGCP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PGCP
Gene ID10404
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Due to its upregulation in hepatocellular carcinoma (HCC), It is a Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides, PGCP is a carboxypeptidase that potentially is involved in the hydrolysis of circulating peptides, PGCP is a member of the Peptidase M28 family of proteins, PGCP is found principally in blood plasma, The gene encoding PGCP maps to chromosome 8, Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis, it is suspected that PGCP may be a potential serological marker for HCC, metallopeptidases and aminopeptidases, which also includes PSM (prostate-specific membrane antigen), which is made up of nearly 146 million bases and encodes about 800 genes, In humans, PGCP is a 472 amino acid secreted protein that is primarily detected in blood plasma
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LDP PGCP
Also known asPGCP Polyclonal Antibody
Other nameAnti-PGCP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPGCP
Short nameAnti-PGCP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PGCP (polyclonal)
Alternative techniquepolyclonals
Identity 16910
Gene CPQ
Long gene name carboxypeptidase Q
Synonyms name lysosomal dipeptidase Ser-Met dipeptidase plasma glutamate carboxypeptidase
Locus 8q22, 1
Discovery year 2012-02-17
GenBank acession AF107834
Entrez gene record 10404
Pubmed identfication 10206990
RefSeq identity NM_016134
Classification Carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000164690

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