Name : Anti-PGGT1A (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4617109529
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PGGT1A |
| Specificity | This antibody reacts specifically with PGGT1A |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human PGGT1A/FNTA |
| Gene ID | 2339 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A is usually but not always an aliphatic amino acid, FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors, It is likely to be a key component of the signaling pathway which involves p21ras, This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence, This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain, also known as CAAX farnesyltransferase (FTase), an important substrate for farnesyltransferase, and X is typically methionine or serine, attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, FNTA |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FPTA PGGT1A PTAR2 |
| Also known as | PGGT1A Polyclonal Antibody |
| Other name | Anti-PGGT1A Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PGGT1A |
| Short name | Anti-PGGT1A (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-PGGT1A (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3782 |
| Gene | FNTA |
| Long gene name | CAAX box, alpha , farnesyltransferase |
| Synonyms name | protein prenyltransferase alpha subunit repeat containing 2 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Locus | 8p11, 21 |
| Discovery year | 1993-04-08 |
| GenBank acession | L10413 |
| Entrez gene record | 2339 |
| Pubmed identfication | 8276393 |
| RefSeq identity | NM_002027 |
| Classification | Prenyltransferase alpha subunit repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000165279 |