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Anti-PGGT1A (Polyclonal), ALEXA Fluor 594

Anti-PGGT1A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePGGT1A
SpecificityThis antibody reacts specifically with PGGT1A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PGGT1A/FNTA
Gene ID2339
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A is usually but not always an aliphatic amino acid, FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors, It is likely to be a key component of the signaling pathway which involves p21ras, This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence, This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain, also known as CAAX farnesyltransferase (FTase), an important substrate for farnesyltransferase, and X is typically methionine or serine, attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, FNTA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FPTA PGGT1A PTAR2
Also known asPGGT1A Polyclonal Antibody
Other nameAnti-PGGT1A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPGGT1A
Short nameAnti-PGGT1A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PGGT1A (polyclonal)
Alternative techniquepolyclonals
Identity 3782
Gene FNTA
Long gene name CAAX box, alpha , farnesyltransferase
Synonyms name protein prenyltransferase alpha subunit repeat containing 2 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Locus 8p11, 21
Discovery year 1993-04-08
GenBank acession L10413
Entrez gene record 2339
Pubmed identfication 8276393
RefSeq identity NM_002027
Classification Prenyltransferase alpha subunit repeat containing
Havana BLAST/BLAT OTTHUMG00000165279

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