Name : Anti-PGGT1B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8821444915
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PGGT1B |
| Specificity | This antibody reacts specifically with PGGT1B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human PGGT1 beta |
| Gene ID | 5229 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 1994 [PubMed 8106351]), MIM 134635) and a 43-kD beta subunit, Mar 2010], The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase, The enzyme is composed of a 48-kD alpha subunit (FNTA, encoded by the PGGT1B gene, Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al, [supplied by OMIM |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | GGTI BGGI |
| Also known as | PGGT1B Polyclonal Antibody |
| Other name | Anti-PGGT1B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PGGT1B |
| Short name | Anti-PGGT1B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, b subunit (polyclonal), antibody to-protein geranylgeranyltransferase classification I |
| Alternative technique | polyclonals |
| Alternative to gene target | BGGI and GGTI, BT, PGGT1B and IDBG-37705 and ENSG00000164219 and 5229, Pggt1b and IDBG-145118 and ENSMUSG00000024477 and 225467, beta subunit, multiple, peptide binding, this GO :0003824 and catalytic activity and molecular function this GO :0004661 and protein geranylgeranyltransferase activity and molecular function this GO :0004662 and CAAX-protein geranylgeranyltransferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005953 and CAAX-protein geranylgeranyltransferase complex and cellular component this GO :0008144 and drug binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0018344 and protein geranylgeranylation and biological process this GO :0019840 and isoprenoid binding and molecular function this GO :0034097 and response to cytokine and biological process this GO :0042277 and peptide binding and molecular function this GO :0045787 and positive regulation of cell cycle and biological process this GO :0051771 and negative regulation of nitric-oxide synthase biosynthetic process and biological process, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004661: protein geranylgeranyltransferase activity and also this GO :0004662: CAAX-protein geranylgeranyltransferase activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding and also this GO :0008270: zinc ion binding and also this GO :0019840: isoprenoid binding and also this GO :0042277: peptide binding, this GO :0004661: protein geranylgeranyltransferase activity, this GO :0004662: CAAX-protein geranylgeranyltransferase activity, this GO :0005515: protein binding, this GO :0008144: drug binding, this GO :0008270: zinc ion binding, this GO :0019840: isoprenoid binding, this GO :0042277: peptide binding, 17618 and IDBG-645000 and ENSBTAG00000001895 and 509322, protein geranylgeranyltransferase type I |
| Identity | 8895 |
| Gene | PGGT1B |
| Long gene name | protein geranylgeranyltransferase type I subunit beta |
| Synonyms gene name | beta subunit , protein geranylgeranyltransferase type I |
| Locus | 5q22, 3 |
| Discovery year | 1997-07-25 |
| Entrez gene record | 5229 |
| Pubmed identfication | 8106351 |
| RefSeq identity | NM_005023 |
| Havana BLAST/BLAT | OTTHUMG00000128893 |