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Anti-PHEX (Polyclonal), ALEXA Fluor 594

Anti-PHEX (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePHEX
SpecificityThis antibody reacts specifically with PHEX
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PHEX
Gene ID5251
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Clinical manifestations include skeletal deformities, PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients, PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption, The PHEX protein, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX, X-linked hypophosphatemic rickets, also designated HYP, and muscular hypotonia with onset in early childhood, craniosynostosis, growth failure, is also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, paravertebral calcifications, pseudofractures in lower extremities, transmembrane and extracellular domain, which is a single-pass membrane protein, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules, The PHEX a 749 amino acid protein that putatively consists of an intracellular
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PEX HPDR1 HYP1 XLH
Also known asPHEX Polyclonal Antibody
Other nameAnti-PHEX Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPHEX
Short nameAnti-PHEX (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PHEX (polyclonal)
Alternative techniquepolyclonals
Identity 8918
Gene PHEX
Long gene name X-linked , phosphate regulating endopeptidase homolog
Synonyms gene HYP HPDR
Synonyms gene name phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
Locus Xp22, 11
Discovery year 1986-01-06
GenBank acession U82970
Entrez gene record 5251
Pubmed identfication 7550339 9070861
RefSeq identity NM_000444
Havana BLAST/BLAT OTTHUMG00000021241
Locus Specific Databases PHEXdb Locus Database

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