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Anti-PHYHIP (Polyclonal), ALEXA Fluor 594

Anti-PHYHIP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePHYHIP
SpecificityThis antibody reacts specifically with PHYHIP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human PHYHIP
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In transgenic mice, PAHX, PHYHIP also interacts with Dyrk1A, PHYHIP interacts with the Refsum disease gene product, Significantly, a protein that that is overexpressed in brain of Down-syndrome patients, breast and several other types of cancers, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, neurologic damage and peripheral neuropathies, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia, small intestine and ovary, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome, which is characterized by cerebellar degeneration, with weak expression in ovary, PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0273 PAHX-AP
Also known asPHYHIP Polyclonal Antibody
Other nameAnti-PHYHIP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPHYHIP
Short nameAnti-PHYHIP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PHYHIP (polyclonal)
Alternative techniquepolyclonals
Identity 16865
Gene PHYHIP
Long gene name phytanoyl-CoA 2-hydroxylase interacting protein
Synonyms gene DYRK1AP3
Synonyms gene name phytanoyl-CoA hydroxylase interacting protein DYRK1A interacting protein 3
Locus 8p21, 3
Discovery year 2001-11-16
GenBank acession D87463
Entrez gene record 9796
Pubmed identfication 9039502 10686344
RefSeq identity NM_014759
Havana BLAST/BLAT OTTHUMG00000163776

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