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Anti-PI 3 Kinase p110 delta (Tyr524), ALEXA Fluor 594

Anti-PI 3 Kinase p110 delta (Tyr524), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePI 3 Kinase p110 delta Tyr524
SpecificityThis antibody reacts specifically with PI 3 Kinase p110 delta (Tyr524)
ModificationPhosphorylation
Modification siteTyr524
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PIK3CD around the phosphorylation site of Tyr524
Gene ID5293
Swiss ProtO00329
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues, CCR7 and S1PR1 and antigen dependent recruitment of T-cells, Contributes to T-helper cell expansion and differentiation, Have a role in NK cell maturation and cytokine production, Have important roles in mast-cell development and mast cell mediated allergic response, Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P), Involved in stem cell factor (SCF)-mediated proliferation, Involved in the antigen presentation function of B-cells, Mediates B-cell proliferation response to anti-IgM, Mediates TCR signaling events at the immune synapse, Mediates immune responses, PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, Participates in NK cell receptor activation, Plays a role in B-cell development, Promotes cytokine production in response to TLR4 and TLR9, Required for B-cell receptor (BCR) signaling, Required for T-cell migration mediated by homing receptors SELL/CD62L, Required for T-cell receptor (TCR) signaling, Required for antibody class switch mediated by TLR9, Required for proliferation, Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation, Together with PIK3CG is involved in neutrophil chemotaxis and extravasation, Together with PIK3CG participates in T-cell development, Together with PIK3CG participates in neutrophil respiratory burst, activating signaling cascades involved in cell growth, adhesion and migration, and function, anti-CD40 and IL4 stimulation, effector and memory T-cells, including AKT1 and PDPK1, migration, motility and morphology, proliferation, proliferation, signaling and cytokine production of naive, survival, 4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 5-trisphosphate (PIP3), Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PIK3CD, Phosphatidylinositol 4, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, 5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4
Also known asPI 3 Kinase p110 delta (Tyr524) Antibody
Other nameAnti-PI 3 Kinase p110 delta (Tyr524)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPI 3 Kinase p110 delta (Tyr524)
Short nameAnti-PI 3 Kinase p110 delta (Tyr524) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PI 3 phosphorylation catalyst p110 delta (Tyr524)

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