Anti-PIGA (Polyclonal), ALEXA Fluor 594

Anti-PIGA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	PIGA
Specificity	This antibody reacts specifically with PIGA
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human PIGA
Gene ID	5277
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, and variable degrees of bone marrow failure, increased tendency to venous thrombosis, the very early intermediate in GPI-anchor biosynthesis, PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	GPI3
Also known as	PIGA Polyclonal Antibody
Other name	Anti-PIGA Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	PIGA
Short name	Anti-PIGA (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-PIGA (polyclonal)
Alternative technique	polyclonals
Identity	8957
Gene	PIGA
Long gene name	phosphatidylinositol glycan anchor biosynthesis class A
Synonyms gene name	class A (paroxysmal nocturnal hemoglobinuria) , phosphatidylinositol glycan
Synonyms name	paroxysmal nocturnal hemoglobinuria phosphatidylinositol N-acetylglucosaminyltransferase
Locus	Xp22, 2
Discovery year	1993-10-28
GenBank acession	BC038236
Entrez gene record	5277
Pubmed identfication	8500164
RefSeq identity	NM_002641
Classification	Glycosyl transferases group 1 domain containing Phosphatidylinositol glycan anchor biosynthesis
Havana BLAST/BLAT	OTTHUMG00000021174
Locus Specific Databases	Mental Retardation database LRG_160

Anti-PIGA (Polyclonal), ALEXA Fluor 594

Anti-PIGA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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