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Anti-PIK3R1(Tyr556) (Polyclonal), ALEXA Fluor 594

Anti-PIK3R1(Tyr556) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePIK3R1 Tyr556
SpecificityThis antibody reacts specifically with PIK3R1(Tyr556)
ModificationPhosphorylation
Modification siteTyr556
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr556 [AE(p-Y)RE]
Gene ID5295
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 4, 5-triphosphate in response to receptor activation in many signal transduction pathways, Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e, p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane, p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues, p85 alpha), The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, g
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GRB1 p85-ALPHA p85
Also known asPIK3R1(Tyr556) Polyclonal Antibody
Other nameAnti-PIK3R1(Tyr556) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPIK3R1(Tyr556)
Short nameAnti-PIK3R1(Tyr556) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PIK3R1(Tyr556) (polyclonal)
Alternative techniquepolyclonals
Identity 8979
Gene PIK3R1
Long gene name phosphoinositide-3-kinase regulatory subunit 1
Synonyms gene name phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Synonyms name phosphoinositide-3-kinase regulatory subunit alpha
Locus 5q13, 1
Discovery year 1992-12-08
GenBank acession M61906
Entrez gene record 5295
Pubmed identfication 1314371 18387942
RefSeq identity NM_181504
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000131251
Locus Specific Databases SH2base: Database for pathogenic SH2 domain mutations LRG_453

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